Two-Mix was formed in 1995 by Minami Takayama, born 5 May 1964 in Tokyo, and Shiina Nagano, born 11 November 1964 in Kumamoto. Takayama served as the duo's vocalist, composer and arranger, while Nagano handled keyboards, composition and lyrics. Their debut single "Just Communication" became the opening theme for the anime Gundam Wing on 29 April 1995, launching the duo into the J-Pop scene. Over the next few years they released a string of singles and albums with King Records, including "Rhythm Emotion" (1995) and the album BPM 150 Max (1996), along with the remix compilation BPM "Dance Unlimited" (1997). In December 1998 they released "Truth – A Great Detective of Love"for Detective Conan, after which they stayed with Warner Music Japan from 1 January 1999, later moving to Little Station in 2003. While Takayama pursued a career as a voice actress, Nagano launched a solo project, ShiinaTactix, in 2008 and briefly reunited with Takayama in 2009 for the double A-side "Lightning Evolution"/"I'm Yours". On 1 May 2012 they announced a return to performing as Two-Mix. Their catalog includes anime themes such as "White Reflection"(1997), used in the film Gundam Wing – Endless Waltz. In July 2022 a tribute album, Crysta-Rhythm, was released, featuring reinterpretations of their songs by other Japanese artists. Two-Mix also received a Japan Gold Disc Award.