Impulse is the podcast where we dive into the most exciting breakthroughs in healthcare of our time. In each episode, we sit down with some of the brightest minds who are using technology to rethink the way we care!
One of the greatest fantasies in medicine is to one day be able to offer any patient a therapy perfectly adapted to their profile and needs. A "personalized" medicine. The term was introduced to the public in 1999 through an article in The Wall Street Journal titled "New Era of Personalized Medicine: Targeting Drugs for Each Unique Genetic Profile." The enthusiasm for these next-generation therapies was fueled by advances in DNA sequencing, which hinted at future discoveries in genomics and rapid progress in medicine. Twenty-five years later, it is clear that personalized medicine has become a reality (e.g., for the treatment of cancer or rare diseases), and technological progress continues to bring us closer to this ideal. But while developing new personalized therapies is one approach, identifying the most effective current therapies for each patient is another, equally powerful one. And thanks to the multimodal analysis capabilities enabled by AI, this field is rapidly expanding. Andre Esteva is one of the pioneers in this area, having significantly advanced medical research in this direction before venturing into entrepreneurship to make this technology available broadly. In less than three years, his company Artera has already achieved many things that most healthtech startups take much longer to reach: The launch of the first AI-based predictive test to evaluate treatment response to hormonal therapy in prostate cancer. The inclusion of the test in the National Comprehensive Cancer Network (NCCN) guidelines nationwide. The obtention of federal reimbursement for the test. In this episode, Andre shares his vision of predictive medicine in the AI era, the potential of this technology for complex diseases such as cancer, and the keys to their success and recognition on the international medical scene! Timeline: 00:03:24 - Andre’s background as a researcher and entrepreneur in medical AI 00:06:01 - The origins of Artera and the vision of personalizing therapy for cancer patients 00:09:29 - Why AI is so relevant for predictive and prognostic medical applications 00:11:51 - How the ArteraAI Prostate Cancer test works 00:19:57 - Getting the test included in national guidelines within a year 00:24:16 - Developing further therapy prediction tests for cancer and beyond 00:26:03 - Lessons learned from securing national reimbursement within two years 00:29:22 - Andre’s view on current and future applications of AI in medicine What we also talked about with Andre: Salesforce H&E stain Prostate-specific antigen Chemotherapy Computer vision Large Language Models (LLMs) AI agents AlphaFold NeurIPS Computer Vision and Pattern Recognition Conference Marc Benioff We cited with Andre some of the past episodes of the series: #43 - Rethinking medical prescriptions to save lives - Emmanuel Bilbault - Posos #41 - Making sense of the gut microbiome - Leo Grady - Jona #40 - Cracking biology through AI - Jean-Philippe Vert - Owkin #36 - Turning healthcare preventive with full-body MRI scans - Andrew Lacy - Prenuvo As Andre mentioned during the episode, you can read their landmark paper published in npj Digital Medicine in 2021 to dive deeper into the technology they have developed. For further information about Artera’s publications and all the scientific work they do, take a look at the News & Insights section of their website. You can follow Artera’s activities on LinkedIn and X, and get in touch with Andre via LinkedIn! If you want to give me feedback on the episode or suggest potential guests, contact me over LinkedIn or via email! And if you liked the episode, please share it, subscribe to the podcast, and leave a 5-star review on streaming platforms! 🙏 There’s now a bi-monthly newsletter around the podcast where you will be informed of the latest episodes and kept posted on the latest medical tech progress, subscribe here! Lastly, don’t forget to follow our activities on LinkedIn and our website!
16/12/2024 • 42:55
To discover the whole episode type "#44 - Predicting cancer treatment response - Andre Esteva - Artera" on your preferred streaming platform.
16/12/2024 • 02:33
According to the WHO, unsafe medication practices and medication errors are a leading cause of avoidable harm in health systems across the globe. In the European Union alone, this translates to nearly 200,000 deaths annually. The magnitude of this problem has led to global initiatives such as "Medication Without Harm," launched in 2017, aiming to reduce medical errors by 50% over five years. Although there is a need for more data on the results of this initiative, we are far from having reached the goal. The key lies in our ability to access medical information, specifically related to prescriptions. Direct access to reliable information, accounting for individual patient characteristics, and able to fit with the tools used by healthcare professionals. A next-generation medical database, incorporating all known information about medications in structured and interoperable bricks capable of supporting caregivers in safer and more effective prescribing practices. It turns out this database exists and has been developed by Pharmacist Emmanuel Bilbault and his team at Posos! Approved less than a year ago by French health authorities, it offers a new perspective on how to approach medical prescriptions in the era of AI and digital health. A way to give back time to every healthcare professional and ensure an unprecedented level of care quality for patients. We talked with Emmanuel about the creation of this new tool - used today by more than 85,000 healthcare professionals in Europe - and what it changes in our fight against medical errors. Timeline: 00:02:56 - What pushed Emmanuel to quit the Pharma industry and found Posos 00:11:11 - The first multilingual, structured, and encoded drug database to streamline medical prescribing 00:16:31 - How Posos is leveraging AI to supercharge its platform 00:22:54 - Keeping the drug database up to date across geographies 00:24:37 - The impact Posos has on healthcare professionals, patients, and health systems 00:29:59 - Toward providing patient access to Posos’ drug database 00:32:40 - Lessons learned from scaling Posos in France and abroad 00:40:47 - Emmanuel’s view on the current healthcare transformation What we also talked about with Emmanuel: Teva Pharmaceuticals IBM’s Watson Health Electronic Health Records SNOMED CT ICD-10-CM ATC MedDRA Named Entity Recognition Optical Character Recognition Word Embedding Machine Learning Pharmagest Ambient AI Nabla We cited with Emmanuel some of the past episodes of the series: #1 - Measuring your arterial age to prevent heart diseases - Ted Baldwin - Imageens As mentioned by Emmanuel during the episode, we recommend taking a look at this page to learn more about the SNOMED CT clinical terminology, as the most comprehensive, multilingual clinical healthcare terminology in the world. You can follow Posos’ activities on LinkedIn, Instagram, and X, and get in touch with Emmanuel via LinkedIn! If you want to give me feedback on the episode or suggest potential guests, contact me over LinkedIn or via email! And if you liked the episode, please share it, subscribe to the podcast, and leave a 5-star review on streaming platforms! 🙏 There’s now a bi-monthly newsletter around the podcast where you will be informed of the latest episodes and kept posted on the latest medical tech progress, subscribe here! Lastly, don’t forget to follow our activities on LinkedIn and our website!
08/12/2024 • 51:05
To discover the whole episode type "#43 - Rethinking medical prescriptions to save lives - Emmanuel Bilbault - Posos" on your preferred streaming platform.
08/12/2024 • 05:33
What will the future of surgery look like? According to Dr. George Papagiannakis, we must count on virtual simulation. After all, simulators are an integral part of professional training in highly demanding fields like aviation or F1. So why not medicine? The approach might seem futuristic, but George and his team at ORamaVR share a vision that makes a lot of sense. Integrating extended reality in surgery means increasing the volume of hours spent operating. It means preparing each surgery on a virtual patient with properties close to the real case. It means simulating complications and unforeseen situations safely. And it means reducing the risk of errors in the real world. Following his motto "never first time with the real patient", George immerses us in the universe of extended reality and reveals its potential for medicine and surgery. What is extended reality? What makes a good virtual medical simulation? And what is the impact of this technology today and in the future? Many questions that George addresses with passion and enthusiasm, in a conversation reminiscent of Ready Player One! Timeline: 02:49 - Addressing the millions of fatal medical errors worldwide 05:20 - Defining extended reality and underlying technologies 07:31 - Medical applications of extended reality 10:52 - The impact of extended reality on medical training and practice 16:25 - What makes a virtual medical environment feel real 23:32 - How to recreate the feel of touch and dexterity virtually 29:28 - Enabling all healthcare professionals to create virtual environments with AI What we also talked about with George: Prof. Shafi Ahmed Apple Vision Pro Magic Leap Microsoft HoloLens NHS The Anatomy Lesson of Dr. Nicolaes Tulp by Rembrandt IKEA Global illumination Dall-E ChatGPT NotebookLM Frost & Sullivan Meta We cited with George some of the past episodes of the series: #9 - Creating the Gran Turismo of surgery - Raimundo Sierra - Virtamed #12 - Unleashing the power of digital health - Daniel Kraft - Digital.Health #32 - Accelerating radiology with AI - Amine Korchi - Radiologist #36 - Turning healthcare preventive with full-body MRI scans - Andrew Lacy As mentioned by George during the episode, we recommend taking a look at some of the simulations available on the official YouTube channel of ORamaVR, it will bring to life many aspects that we discuss in the episode! You can follow ORamaVR’s activities on LinkedIn, Instagram, and get in touch with George via LinkedIn! If you want to give me feedback on the episode or suggest potential guests, contact me over LinkedIn or via email! And if you liked the episode, please share it, subscribe to the podcast, and leave a 5-star review on streaming platforms! 🙏 There’s now a bi-monthly newsletter around the podcast where you will be informed of the latest episodes and kept posted on the latest medical tech progress, subscribe here! Lastly, don’t forget to follow our activities on LinkedIn and our website!
02/12/2024 • 41:50
To discover the whole episode type "#42 - Extending reality to transform surgery - George Papagiannakis - ORamaVR" on your preferred streaming platform.
02/12/2024 • 03:00
Our gut contains a world of microorganisms that impact many aspects of our health, well beyond the gastrointestinal system. In fact, more than 30 trillion bacteria, archaea, fungi, and viruses live in the digestive tract of every human, a number that is higher than the number of human cells that make up our body! Each microbiome is unique to an individual, and its genetic heritage represents approximately 100 times that of the human genome. This field is fascinating and science is advancing rapidly, as evidenced by the 2,000 publications generated monthly on the subject. A better understanding of this remarkable ecosystem might bring critical answers to address numerous pathologies and health disorders. This is the mission of Leo Grady and his team at Jona, whose technology enables microbiome analysis based on an at-home test, combined with artificial intelligence to reveal what the current literature says about each person's microbiome. Unveiling the propensity for certain disease risks, along with individual nutritional preferences, Jona can model the body's reaction according to potential changes in the microbiome, and provide valuable insights on behaviors and nutrition that can ultimately improve one’s health. A dive into the heart of the microbiome and its secrets, which today's technology is about to unlock! Timeline: 02:32 - Leo’s journey from his PhD in computer vision to AI applications in medicine 06:47 - The idea behind Jona and understanding the microbiome better 10:33 - What we do know and ignore about the microbiome 13:05 - The Jona test kit and what it can interpret from one’s microbiome picture 20:17 - The volume and complexity of studies around the microbiome 22:11 - The impact of Jona and Leo’s son's story 25:38 - Who is Jona for 29:00 - Leo’s vision for the future of Jona and AI in healthcare What we also talked about with Leo: Neural networks Siemens HeartFlow Paige AI Memorial Sloan Kettering Crohn’s disease Thomas Clozel We cited with Leo some of the past episodes of the series: #32 - Accelerating radiology with AI - Amine Korchi - Radiologist #35 - Making surgery smarter and safer - Björn Von Siemens - Caresyntax #36 - Turning healthcare preventive with full-body MRI scans - Andrew Lacy - Prenuvo #40 - Cracking biology through AI - Jean-Philippe Vert - Owkin As mentioned by Leo during the episode, we recommend looking at the Jona Journal which sheds light on the latest findings on the microbiome fueled by their research platform, and understanding the current literature. Leo also recommends listening to The Mind-Gut Conversation Podcast by Emeran Meyer to find out more, and We Contain Multitudes by Sarah Henstra as a complementary read. You can follow Jona’s activities on LinkedIn, X, Instagram, and YouTube, and get in touch with Leo via LinkedIn. If you want to give me feedback on the episode or suggest potential guests, contact me over LinkedIn or via email! And if you liked the episode, please share it, subscribe to the podcast, and leave a 5-star review on streaming platforms! 🙏 There’s now a bi-monthly newsletter around the podcast where you will be informed of the latest episodes and kept posted on the latest medical tech progress, subscribe here! Lastly, don’t forget to follow our activities on LinkedIn and our website!
26/11/2024 • 47:19
To discover the whole episode type "#41 - Making sense of the gut microbiome - Leo Grady - Jona" on your preferred streaming platform.
26/11/2024 • 05:03
All experts agree: if there's one sector that AI will transform, it's healthcare. Whether it's understanding pathologies, developing personalized treatments, the doctor-patient relationship, diagnostic methods, or creating tools to facilitate the work of healthcare professionals, everything is affected by the ongoing transformation! This revolution raises many expectations and questions about the real impact these new technologies will have on tomorrow's medicine. One of the leading figures in this movement on the international scene is none other than the French-American company Owkin, which aims to be "the first end-to-end AI biotech company," whose R&D activities are overseen by Jean-Philippe Vert, himself a true pioneer in the field of machine learning and computational biology. The first “AI-first” biotech company of its kind, bringing a breath of fresh air to an industry known for being extremely costly and time-consuming. So how does AI accelerate the development of new therapies? What is its role in identifying new molecules and targets? How can it be used to create new diagnostic tools? Can we leverage patient data without compromising their safety and privacy? And what can we expect from future models and their impact on our understanding of biology? These are all fascinating questions that Jean-Philippe breaks down with pedagogy and realism, shedding light on one of the most exciting fields of medicine in this era! Timeline: 04:21 - Jean-Philippe’s background at the interface of mathematics, computer science, and life sciences 07:10 - Owkin’s mission to become the first end-to-end AI biotech firm 09:48 - Leveraging AI for drug discovery and new treatment modalities 14:35 - Selecting target indications and therapeutic areas 17:13 - Changing the way we run clinical trials through AI 22:03 - Unlocking patient data across hospitals while preserving safety and privacy 25:40 - Developing AI-based diagnostics and driving clinical adoption 34:50 - Towards the first AI foundation model to understand biology What we also talked about with Jean-Philippe Google DeepMind Large Language Models (LLMs) Digital twins External control arms Federated learning Digital pathology MSIntuit CRC Bioptimus Neural networks As mentioned by Jean-Philippe during the episode, we recommend taking a look at Owkin and Bioptimus websites as well as their respective Publications & News section to learn more about their technology and stay posted on their latest activities. If you are a data scientist or machine learning enthusiast, you can tackle one of the many biology-related challenges proposed by Kaggle on their platform. To learn more about Owkin’s portfolio and the diversity of biomarkers and health conditions they cover, take a look at their Pipeline section. You can follow Owkin’s activities on LinkedIn, X, and YouTube, and Bioptimus on LinkedIn and X. To get in touch with Jean-Philippe, contact him over LinkedIn. If you want to give me feedback on the episode or suggest potential guests, contact me over LinkedIn or via email! And if you liked the episode, please share it, subscribe to the podcast, and leave a 5-star review on streaming platforms! 🙏 There’s now a bi-monthly newsletter around the podcast where you will be informed of the latest episodes and kept posted on the latest medical tech progress, subscribe here! Lastly, don’t forget to follow our activities on LinkedIn and our website!
18/11/2024 • 51:44
To discover the whole episode type "#40 - Cracking biology through AI - Jean-Philippe Vert - Owkin" on your preferred streaming platform.
18/11/2024 • 05:35
Among pioneering companies in connected health devices, few have been as forward-thinking as Withings, a flagship of French technology. Their first connected scales date back to 2009 (when smartphones were still emerging!) and remain the industry standard today. For that time, it was a subtle blend combining sleek design, intuitive user experience, and medical precision. A formula that Withings has successfully applied and developed in many other areas, from smartwatches to sleep sensors, thermometers, blood pressure monitors, or even a urinalysis device for your toilet! Their portfolio covers a wide range of medical parameters and helps hundreds of thousands of individuals manage their health daily. Matthieu Menanteau is one of the minds behind Withings' creations over the past 8 years. In this highly insightful episode, he shares Withings' philosophy and approach to creating the ultimate connected health experience, one that allows everyone to better understand themselves and take control of their health journey. We discuss: Withings' philosophy to innovate successfully in today's connected health sector Three development pillars that form the essence of Withings products The ongoing integration of consumer health with health systems and telemedicine The power of continuous medical data in the age of AI and big data A conversation that brings new perspectives on the future of connected health, and how technology can integrate into our daily lives to guide us toward healthier behaviors! Timeline: 03:45 - Withings’ origins and vision for connected health 07:18 - Providing the ultimate health companion 10:03 - Biomarkers and indications covered by Withings 13:11 - A home urinalysis laboratory 17:44 - Bringing the medical check-up at home 21:11 - A dual approach to driving innovation in connected health 26:20 - Towards an overwhelming mass of connected health devices? 31:47 - Withings’ three pillars of product development 38:05 - The role of AI in creating the ultimate connected health experience What we also talked about with Matthieu: Type 2 diabetes Lean mass Visceral fat Hydration pH Vitamin C Ketones Oxygen saturation Cuffless blood pressure measurement Apple CE mark FDA Edge computing Doctolib Alan CES We cited with Matthieu some of the past episodes of the series: #21 - Transforming hypertension care with a bracelet - Jay Shah - Aktiia #23 - Disrupting the smart wearables industry - Leo Grünstein - Spiden As mentioned by Matthieu during the episode, we recommend taking a look at the Research section of the Withings website, to learn more about current and future publications surrounding their products. To learn more about their portfolio and the diversity of biomarkers and health conditions they cover, take a look at their Products section. You can follow Withings’ activities on LinkedIn, X, Instagram, and YouTube, and get in touch with Matthieu via LinkedIn. If you want to give me feedback on the episode or suggest potential guests, contact me over LinkedIn or via email! And if you liked the episode, please share it, subscribe to the podcast, and leave a 5-star review on streaming platforms! 🙏 There’s now a bi-monthly newsletter around the podcast where you will be informed of the latest episodes and kept posted on the latest medical tech progress, subscribe here! Lastly, don’t forget to follow our activities on LinkedIn and our website!
10/11/2024 • 52:30
To discover the whole episode type "#39 - Crafting the best connected health experience - Matthieu Menanteau - Withings" on your preferred streaming platform
10/11/2024 • 05:42
Medical biology and laboratories play an essential role in any health system. No wonder 70 to 80% of all medical decisions are based on laboratory test results. But even within the most advanced healthcare systems, the communication and analysis of lab data remain archaic. Processing times can be lengthy, even after the analysis is completed. Results are expressed as "out of range" or "in range", without complementary or actionable information. An experience still far from current technological standards, and a gap that Alexandre Guenoun and his team at Kiro intend to solve by redefining our experience of medical biology! Through faster and more personalized results for patients. With a suite of integrated clinical decision support tools for healthcare professionals. And a longitudinal database to accelerate biomedical research. A key service of any health system, at a turning point in France and beyond. We talk with Alexandre about: The importance of engaging each individual in their health journey The shift from disease-centered medicine to service-centered The Kiro experience for patients and healthcare professionals The role of technology in matching healthcare demand and supply The criticality of change management in healthcare innovation A key episode to understand the future of medical biology! Timeline: 02:57 - What drew Alexandre to healthcare and entrepreneurship 08:41 - How technology can make clinical biology smarter and more personalized 11:24 - The Kiro experience for patients and healthcare professionals 24:56 - Interpreting medical biology data with AI 28:16 - Matching demand and supply in health systems 31:01 - Scaling Kiro in Europe and beyond 34:01 - Leading change management with healthcare professionals What we also talked about with Alexandre: ZEBRA MEDICAL ESSEC Business School UC Berkeley Agoranov GPT-4o Sacha Loiseau This episode is brought to you in collaboration with Health.Tech, the heartbeat of healthtech! As mentioned by Alexandre during the episode, you can have a look at Kiro’s Product page to understand better their technology and stay posted on their latest progress. Alexandre also recommends reading The Hard Thing About Hard Things: Building a Business When There Are No Easy Answers by Ben Horowitz. You can follow Kiro's activities on LinkedIn and get in touch with Alexandre via LinkedIn. If you want to give me feedback on the episode or suggest potential guests, contact me over LinkedIn or via email! And if you liked the episode, please share it, subscribe to the podcast, and leave a 5-star review on streaming platforms! 🙏 There’s now a bi-monthly newsletter around the podcast where you will be informed of the latest episodes and kept posted on medical tech progress, subscribe here! Lastly, don’t forget to follow our activities on LinkedIn and our website!
04/11/2024 • 49:20
To discover the whole episode type "#38 - Rethinking medical biology with AI - Alexandre Guenoun - Kiro" on your preferred streaming platform.
04/11/2024 • 04:20
Can the attention economy be harnessed to serve health? Paradoxical as it may seem, this is the thesis of Tryggvi Thorgeirsson and his team at Sidekick Health. As a medical doctor trained in Iceland in the 2000s, Tryggvi experienced rural medicine firsthand and what working as a general practitioner in a remote setting means. And he quickly found himself confronted with the limitations posed by the healthcare system at the time: Prescribing medications at the expense of other therapies where patients are guided toward healthier behaviors. The silos and impossibility of establishing a care plan that simultaneously takes into account multiple conditions. A purely reactive approach based on a brick-and-mortar model running out of steam. The emergence of smartphones and their potential as health companions became obvious to him. Based on this intuition, he co-founded Sidekick Health alongside his fellow physician and colleague Saemundur Oddsson. The company is now one of the leaders in digital therapeutics, offering a vast portfolio of therapies accessible from each patient's pocket, prescribed by thousands of doctors in Europe and the US. We talk with Tryggvi about the principles behind how these digital therapies work, how attention levers can be used to support long-term behavior change, and the growing impact these solutions have on individuals and healthcare systems. In the era of social media and the mental plague they represent, this episode brings a refreshing perspective on how dopamine can be used to put the health of individuals back in their own hands. Timeline: 02:35 - Tryggvi’s background as a medical doctor and electrical engineer 04:05 - What felt missing in Tryggvi’s rural medical practice 07:14 - Seeing early the potential of smartphones for healthcare 11:08 - Tryggvi’s definition of digital therapeutics 13:44 - The impact of digital therapeutics on clinical outcomes and cost of care 16:44 - Driving behavioral change and medical education through timely bite-sized pieces and gamification 18:40 - Sidekick Health’s approach to designing tailored and impactful digital health programs across multiple conditions 27:46 - Putting AI at the center of digital health programs and their usage 30:13 - Tryggvi’s vision for the future of healthcare What we also talked about with Tryggvi: PINK! Prof. Pia Wülfing Pear Therapeutics Daniel Kahneman Harvard T.H. Chan School of Public Health We cited with Tryggvi some of the past episodes of the series: #7 - Redefining motor rehabilitation with digital neurotherapeutics - Naveed Ejaz - MindMaze #17 - Coaching as the key to a better health - Eugene Borukhovich - YourCoach.Health #30 - Building the Shopify of digital health - Dan Vahdat - Huma As mentioned by Tryggvi during the episode, we recommend reading Exits & Outcomes by Brian Dolan as well as Second Opinion by Christina Farr, two newsletters that will keep you posted on the latest in digital health. To dive further into the programs and use cases around Sidekick Health’s technology, take a look at their website. You can follow Sidekick Health’s activities on LinkedIn and X, and get in touch with Tryggvi via LinkedIn. If you want to give me feedback on the episode or suggest potential guests, contact me over LinkedIn or via email! And if you liked the episode, please share it, subscribe to the podcast, and leave a 5-star review on streaming platforms! 🙏 There’s now a bi-monthly newsletter around the podcast where you will be informed of the latest episodes and kept posted on the latest medical tech progress, subscribe here! Lastly, don’t forget to follow our activities on LinkedIn and our website!
30/10/2024 • 44:20
To discover the whole episode type "#37 - Hacking the dopamine system for good - Tryggvi Thorgeirsson - Sidekick Health" on your preferred streaming platform.
30/10/2024 • 03:36
Making healthcare preventive and better able to catch serious conditions earlier is a recurring topic for governments, health systems, and ultimately patients. As healthcare resources become scarce while chronic conditions and their burden on society grow larger, a preventive and more proactive approach to healthcare is undoubtedly part of the solution. There are many ways to go about it, with one emerging trend over the past few years focusing on holistic check-ups, providing a large set of scans, biological assays, and complimentary exams all at once on the same day, helping to give a broad snapshot of one’s health status. One approach that has triggered debate within the medical community focuses on full-body MRI scans delivered to individuals who can afford it, as the ultimate disease prevention tool. A detailed view of the inside of one’s body, based on one of the most widely used medical imaging methods. Some criticize the lack of evidence around the true benefits these scans bring to patients and health systems, pointing to the high price charged for them. Others testify to the diagnostic help these scans offer, lifting the veil on previously unexplained patient cases, and highlighting the possibility of taking action long before certain symptoms are expressed. One way or another, these reactions reflect an approach to medical screening that challenges traditional practices and raises questions. In this episode with the Founder and CEO of Prenuvo, Andrew Lacy addresses the main questions raised by this practice, offering new perspectives on how to apprehend these scans as a medical analysis tool, how they can complement existing care practices, and the complexity linked to the evaluation of the impact that these scans can have on health systems. An eye-opening conversation on what might constitute a part of future preventive healthcare! Timeline: 00:02:47 - Andrew’s background as a serial tech entrepreneur and his move into healthcare 00:04:15 - The idea behind Prenuvo and full-body scans as an early medical screening method 00:06:49 - What the Prenuvo experience looks like compared to a typical medical check-up 00:10:11 - The Prenuvo scanner and what it can see inside the body 00:14:41 - Can Prenuvo scans diagnose certain conditions? 00:18:44 - For whom are these scans for? 00:21:35 - Building the case for full-body MRI scans benefits toward health systems 00:25:39 - Making full-body MRI scans more affordable 00:27:30 - How Prenuvo leverages AI throughout its operations 00:30:21 - Empowering patients to drive long-term behavioral change 00:34:43 - Prenuvo’s plans for geographic expansion and growth What we also talked about with Andrew: Dr. Raj Attariwala This episode was made possible with the support of HLTH Europe! As mentioned by Andrew during the episode, we recommend taking a look at the Research section of Prenuvo’s website, to be informed about the latest in multi-parametric MRI studies and its applications across multiple disease areas. You can also find out more on PubMed for further studies on these topics. To dive further into the technology behind Prenuvo’s scans, head out to The Scan section of their website. You can follow Prenuvo’s activities on LinkedIn, Instagram, and X, and get in touch with Andrew via LinkedIn. If you want to give me feedback on the episode or suggest potential guests, contact me over LinkedIn or via email! And if you liked the episode, please share it, subscribe to the podcast, and leave a 5-star review on streaming platforms! 🙏 There’s now a bi-monthly newsletter around the podcast where you will be informed of the latest episodes and kept posted on the latest medical tech progress, subscribe here! Lastly, don’t forget to follow our activities on LinkedIn and our website!
24/10/2024 • 47:45
To discover the whole episode type "#36 - Turning healthcare preventive with full-body MRI scans - Andrew Lacy - Prenuvo" on your preferred streaming platform.
24/10/2024 • 04:22
Modernizing surgery by making it smarter, safer, and more predictive. This is the mission of Björn Von Siemens and his team at Caresyntax. By developing a platform that integrates into hospitals’ infrastructures and leveraging their data flows throughout the planning, execution, and follow-up of surgeries, the company has established itself as a leader in connected surgery. Their impact on health systems worldwide is massive and continues to grow at pace: +3000 equipped operating rooms +30,000 surgical teams served +3 million surgeries assisted each year In a world where healthcare resources are growing scarce and where access to surgery is highly unequal, Caresyntax aims to be one of those enabling a profound change in medicine at scale, for the benefit of patients, healthcare professionals, and hospitals. By helping them optimize the use of operating rooms, staffing, and costs. By providing video oversight and intelligence for each operation performed, tracking every step of their execution. By enabling continuous improvement of medical teams and surgeons through detailed case reviews. In this fascinating episode, we delve into the world of cutting-edge surgery in the era of robotics, AI, and automation. Björn opens up about the inside story of this unique healthtech entrepreneurial adventure, revealing the challenges and successes that have made Caresyntax a pillar of modern surgery! Timeline: 00:02:45 - Bjoern’s story as an aspiring surgeon who shifted toward healthcare entrepreneurship 00:08:14 - The idea behind Caresyntax and solving major needs for surgery 00:14:16 - The functioning of Caresyntax’s platform 00:18:07 - Helping surgeons get better at what they do 00:26:45 - Giving transparency to hospitals on their operations and opportunities for improvement 00:31:55 - The role of AI in Caresyntax’s platform 00:34:44 - Helping hospitals fight the burn-out crisis 00:39:08 - Setting the right expectations from patients prior to surgery 00:42:39 - What excites Björn for the future of surgery What we also talked about with Björn: Quantum Surgical Intuitive Surgical Radical prostatectomy Total knee arthroplasty Neuralink General Catalyst We cited with Björn some of the past episodes of the series: #2 - Treating liver cancer with surgical robotics - Lucien Blondel - Quantum Surgical This episode was made possible with the support of HLTH Europe! As mentioned by Björn during the episode, we recommend reading The Checklist Manifesto: How to Get Things Right by Atul Gawande. To dive further into the applications and use cases around Caresyntax’s platform for surgery, take a look at the Resources section of their website. You can follow Caresyntax’s activities on LinkedIn and X, and get in touch with Björn via LinkedIn. If you want to give me feedback on the episode or suggest potential guests, contact me over LinkedIn or via email! And if you liked the episode, please share it, subscribe to the podcast, and leave a 5-star review on streaming platforms! 🙏 There’s now a bi-monthly newsletter around the podcast where you will be informed of the latest episodes and kept posted on the latest medical tech progress, subscribe here! Lastly, don’t forget to follow our activities on LinkedIn and our website!
13/10/2024 • 55:47
To discover the whole episode type "#35 - Making surgery smarter and safer - Björn Von Siemens - Caresyntax" on your preferred streaming platform.
13/10/2024 • 04:37
Leaving your surgical training to create a healthcare conference from scratch... ...On an island of 300 km² in the middle of the Mediterranean! This is the crazy bet that Dylan Attard took 5 years ago by founding MedTech World. From its first online conference held in 2020 in the midst of COVID-19 to its early roadshows around the world two years later, the annual Maltese event led by Dylan and his team has now established itself as a must on the global healthtech scene! Far from traditional trade shows sponsored by industry giants, MedTech World aims to be a platform to accelerate healthcare innovation by fostering an intimate connection between entrepreneurs, investors, HCPs, and industry professionals. This year, more than 2000 participants will gather at the Mediterranean Conference Center (a building built as a hospital in the 16th century!), including more than 300 startups, 100 investors, and 200 partners. So how do we plan such an event? How to curate its content to create value for its participants and partners? What does it take to build a strong community centered on medical innovation? And how to differentiate yourself from other global conferences? In this Masterclass on healthcare event management, Dylan unveils the keys to MedTech World's success and many more reasons to join in in Malta in November this year! Timeline: 00:02:36 - Dylan’s background from surgery trainee to founding a global conference 00:06:12 - Mutual benefits of having a medical background and being an entrepreneur 0009:03 - The idea behind MedTech World 00:16:01 - Attractivity of Malta as a medical technology hub 00:18:20 - Expanding MedTech World’s reach beyond Malta 00:20:51 - Shaping the conference program and curating the highest quality content 00:27:17 - Trends and emerging technologies in MedTech worth following 0029:36 - Dylan’s advice on making a career change from medical professional to entrepreneur What we also talked about with Dylan: Malta Medical Students’ Association Prof. Shafi Ahmed We mentioned with Dylan some of the past episodes of the series: #2 - Treating liver cancer with surgical robotics - Lucien Blondel This episode was made possible with the support of MedTech World! As Dylan mentioned during the episode, you can learn more about the different events that MedTech World hosts throughout the year on their official website. To register for the conference in Malta, click here and use the code MTWMaltaMathieuChaffard150OFF to get 150€ off your attendance ticket! You can follow MedTech World’s activities on LinkedIn, X, and Instagram, and contact Dylan via LinkedIn. If you want to give me feedback on the episode or suggest potential guests, reach out via LinkedIn or email! And if you liked the episode, please share it, subscribe to the podcast, and leave a 5-star review on streaming platforms! 🙏 There’s now a bi-monthly newsletter around the podcast where you will be informed of the latest episodes and kept posted on the latest medical tech progress, subscribe here! Lastly, don’t forget to follow our activities on LinkedIn and our website!
07/10/2024 • 41:21
To discover the whole episode type "#34 - Uniting to bring medical technology forward - Dylan Attard - MedTech World" on your preferred streaming platform.
07/10/2024 • 04:25
AI and computational science are revolutionizing the biotechnology sector. From identifying new therapeutic approaches to their production and accelerating the administrative processes for bringing them to market, the entire value chain of this sector is impacted! These recent advancements have given rise to a new field in the industry: TechBio. But what lies behind this futuristic term? And how exactly do these technologies accelerate the development and introduction of new treatments? These two questions are at the heart of this episode featuring Mati Gill from AION Labs. With a background in law and in the pharmaceutical industry, Mati is the CEO of this venture builder focused on this emerging field, at the cutting edge of computer science and biology. A true startup factory for TechBio, formed around partnerships with the world's largest Tech and Biotechnology companies. Unlike conventional innovation platforms such as incubators or startup accelerators, AION Labs enables Founders to accelerate the development of their companies through a holistic range of services and tools: Anchoring the startup’s mission around a clear R&D issue identified by industrial partners Funding new ventures at the pre-seed or seed stage Assisting Founders in identifying and recruiting talent Providing the infrastructure and resources necessary for co-developing new solutions with industrial partners A masterclass on innovation in TechBio and what this industry will change for health and patients soon! Timeline: 00:02:43 - Mati’s background from studying law to entering the TechBio field 00:07:00 - A new way to discover medical treatments and drugs 00:12:42 - The current impact of TechBio on the pharmaceutical industry 00:15:58 - The attitude of regulators toward TechBio and how they adapt to it 00:19:00 - Breaking down fantasies around TechBio and its promises 00:23:54 - AION Lab’s operating model and how to build the next TechBio success 00:34:06 - Relationships and investments between startups and partners from AION Labs 00:41:30 - Advice for TechBio enthusiasts and future entrepreneurs in the field What we also talked about with Mati: Sharon Kredo-Russo Nature’s article on AI’s potential to accelerate drug discovery (from October 2023) FDA EMA DenovAI Biotech Kashif Sadiq PromiseBio Prof. Yifat Merbl We cited with Mati some of the past episodes of the series: #8 - Using organoids to transform drug discovery - Nikolce Gjorevski - Roche This episode was made possible with the support of HLTH Europe! As Mati mentioned during the episode, you can learn more about the latest in TechBio through Christian Tidona’s work with Biomed X. You can follow AION Labs’ activities on LinkedIn and X, and get in touch with Mati via LinkedIn. If you want to give me feedback on the episode or suggest potential guests, contact me over LinkedIn or via email! And if you liked the episode, please share it, subscribe to the podcast, and leave a 5-star review on streaming platforms! 🙏 There’s now a bi-monthly newsletter around the podcast where you will be informed of the latest episodes and kept posted on the latest medical tech progress, subscribe here! Lastly, don’t forget to follow our activities on LinkedIn and our website!
29/09/2024 • 53:16
To discover the whole episode type "#33 - Building the next TechBio venture - Mati Gill - AION Labs" on your preferred streaming platform.
29/09/2024 • 06:04
Radiology is the field of medicine that has experienced some of the most dramatic technological changes over the past decades. And given the record number of approvals for AI-based and machine-learning tools dedicated to radiology in Europe and the US (far ahead of all other medical specialties combined!), this trend is unlikely to slow down. Such rapid evolution can be attributed to the abundance of imaging data from clinical practice, and it already has a huge impact on the way radiologists work and care for patients. Faster workflows, enhanced diagnostic accuracy, and better informed clinical decisions… As we enter the era of multimodal AI models capable of simultaneously interpreting volumes of data from different formats (such as voice notes, images, videos, texts, etc.), we can only expect this evolution to accelerate even more in the coming months and years. As we seek to understand this transformation, we sit down with Amine Korchi, a Swiss radiologist, entrepreneur, investor, and renowned advocate for technological progress in radiology. In this eye-opening episode, Amine offers us a rich perspective on: the evolution of medical imaging, from static 2D images, through dynamic 3D, to AI the impact of AI on the training of physicians and their specialization current use cases of AI in radiology and their impact on patient care the barriers to its adoption and the fears AI raises among radiologists future developments of AI in radiology and their promises An episode to help us understand one of the major technological revolutions in medicine - and one we're far from seeing the end of! Timeline: 00:02:39 - Amine’s background as a radiologist, entrepreneur, and investor in clinical AI 00:06:10 - How radiology transformed over the past 20 years 00:13:43 - Is ultra specialization in medicine a good thing? 00:17:39 - Concrete use cases of AI in clinical radiology 00:21:50 - Barriers to AI adoption in radiology 00:27:44 - Future developments of AI in radiology 00:33:17 - The tasks that AI will replace in radiology 00:36:16 - Impact of AI on future radiologists’ training What we also talked about with Amine: Intravenous urography CT Scan Iseult MRI machine Tumor board GPT4-o Cerebriu Smart Reporting Gleamer Owkin Kicky Van Leeuwen Hugh Harvey Microlearning We mentioned with Amine some of the past episodes of the series: #1 - Measuring your arterial age to prevent heart diseases - Ted Baldwin - Imageens #16 - Making ultrasound portable to transform medical imaging - Ohad Arazi - Clarius As mentioned by Amine during the episode, you can learn more about the latest in radiology through The Imaging Wire newsletter or on Radiology Business. If you want to get in touch with Amine, you can do so via LinkedIn. If you want to give me feedback on the episode or suggest potential guests, contact me over LinkedIn or via email! And if you liked the episode, please share it, subscribe to the podcast, and leave a 5-star review on streaming platforms! 🙏 There’s now a bi-monthly newsletter around the podcast where you will be informed of the latest episodes and kept posted on the latest medical tech progress, subscribe here! Lastly, don’t forget to follow our activities on LinkedIn and our website!
22/09/2024 • 54:48
To discover the whole episode type "#32 - Accelerating radiology with AI - Amine Korchi - Radiologist" on your streaming platform.
22/09/2024 • 02:35
Sleep is the resting state that nature has chosen for us by default. Long overlooked or even neglected, it is one of the keys to good health, alongside nutrition, physical exercise, and mental and emotional health. Moreover, it is an excellent indicator of our overall health: when our sleep is disturbed, it usually means at least one of these four components is affected. It thus seems essential to be able to measure the quality of our sleep while minimizing the interaction or invasiveness of the measurement method with our body. And that is precisely the promise of Soumya Dash and his company Sleepiz! Based on radar technology, this Swiss startup has developed a compact device to place on a bedside table, capable of remotely clinically measuring sleep and detecting potential disorders such as sleep apnea or insomnia. No electroencephalogram to wear on the head, no pulse oximeter on the finger, nor any wearable around the wrist: everything is measured from the bedside table and without any direct interaction with the subject measured. In this surprising episode, we dive into the fascinating world of sleep, a realm with many secrets still to be uncovered! Soumya shares with us insights into the technology his team has developed, the difference between consumer-grade and medical-grade sleep monitors, and a glimpse into the future of healthcare in this field! Timeline: 00:02:21 - How Soumya came across sleep monitoring and why it matters 00:12:45 - How the Sleepiz device monitors sleep 00:18:20 - Relevant use cases and target indications of sleep disorders 00:22:35 - Differences between consumer-grade vs. medical-grade sleep monitors 00:25:35 - B2C and B2B business models 00:37:43 - Past milestones and challenges ahead What we also talked about with Soumya: ETH Zürich ISO 13485 norm Class IIa medical device 510(k) FDA clearance Chronic Obstructive Pulmonary Disease (COPD) Oura Ring WHOOP IDUN Technologies SmartCardia As mentioned by Soumya during the episode, you can learn more about sleep and the current state of research in the book Why We Sleep: Unlocking the Power of Sleep and Dreams by Matthew Walker. You will find more information about Sleepiz on their website and you can follow their activities on LinkedIn. If you want to get in touch with Soumya, you can do so via LinkedIn. If you want to give me feedback on the episode or suggest potential guests, contact me over LinkedIn or via email! And if you liked the episode, please share it, subscribe to the podcast, and leave a 5-star review on streaming platforms! 🙏 There’s now a bi-monthly newsletter around the podcast where you will be informed of the latest episodes and kept posted on the latest medical tech progress, subscribe here! Lastly, don’t forget to follow our activities on LinkedIn and our website!
15/09/2024 • 54:51
To discover the whole episode type "#31 - Measuring sleep remotely - Soumya Dash - Sleepiz" on your streaming platform.
15/09/2024 • 02:51
Dan Vahdat is an emblematic figure and entrepreneur in healthtech. A visionary we could say, having anticipated the problem of point solutions in the industry, while predicting the essential role smartphones would have in empowering patients to take control of their health. The company he founded after pausing his PhD, Huma, has pioneered the field of digital health and remote patient monitoring, having been one of the first to successfully deliver digital disease management programs across multiple conditions. The first to receive regulatory clearance in Europe (IIb) and the US (II) for its configurable disease management platform. As the firm is nearing the status of “unicorn” in its 13th year and approaching profitability, it’s never been so close to realizing Dan’s vision: augmenting the capacity of health systems at scale while enabling true proactive and predictive care. Huma’s list of successes is immense: more than 3000 hospitals and clinics supported, 27 million patients served, Winner of the 2022 Prix Galien award for digital health, and the list goes on… But the Founder’s ambition does not stop there. In this fascinating episode, Dan explains Huma’s journey toward becoming the “Shopify” of digital health, or in other words, the central infrastructure on which other digital health companies can successfully build disease management programs, more efficiently and at less cost. In the challenging business of digital health, Dan shares his reflections on what enabled Huma to succeed where many other companies failed. He explains the approach they took when it comes to fostering patient engagement, addressing healthcare professionals’ needs, and being relentless about building robust clinical and economic evidence. An inside look into one of the most innovative firms in digital health, and the future of this industry! Timeline: 00:03:04 - Dan’s background from dropping out of his PhD to founding Huma 00:06:16 - Huma’s starting point focusing on rare diseases 00:08:09 - The Huma platform and how it is changing how we deliver care 00:10:56 - Creating the Shopify for digital health 00:17:25 - How Huma is improving running decentralized clinical trials 00:21:53 - The importance of UX and evidence generation 00:24:42 - Making engaging digital health solutions 00:28:14 - What excites Dan for digital health’s future 00:34:02 - Dan’s reflections on his journey from PhD dropout to Huma’s CEO 00:37:40 - Maximizing operational efficiency in a healthtech startup What we also talked about with Dan: Second Opinion Peterson Technology Health Institute Elon Musk by Walter Isaacson 23andme Vertex Pharmaceuticals We cited with Dan some of the past episodes of the series: #21 - Transforming hypertension care with a bracelet - Jay Shah - Aktiia #23 - Disrupting the smart wearables industry - Leo Grünstein - Spiden This episode was made possible with the support of HLTH Europe! As mentioned by Dan during the episode, you can join the waitlist for the Huma Cloud Platform here. You will find on their website more information about their latest news and research. You can follow Huma’s activities on LinkedIn and X, and get in touch with Dan via LinkedIn. If you want to give me feedback on the episode or suggest potential guests, contact me over LinkedIn or via email! And if you liked the episode, please share it, subscribe to the podcast, and leave a 5-star review on streaming platforms! 🙏 There’s now a bi-monthly newsletter around the podcast where you will be informed of the latest episodes and kept posted on the latest medical tech progress, subscribe here! Lastly, don’t forget to follow our activities on LinkedIn and our website!
08/09/2024 • 48:43
To discover the whole episode type "#30 - Building the Shopify of digital health - Dan Vahdat - Huma" on your streaming platform.
08/09/2024 • 02:51
